



{"id":604,"date":"2024-05-05T05:47:57","date_gmt":"2024-05-05T05:47:57","guid":{"rendered":"https:\/\/calerie-energysystem.info\/?p=604"},"modified":"2025-03-06T09:00:28","modified_gmt":"2025-03-06T09:00:28","slug":"tong-hop-ve-nmn","status":"publish","type":"post","link":"https:\/\/calerievn.com\/index.php\/2024\/05\/05\/tong-hop-ve-nmn\/","title":{"rendered":"NMN- D\u01af\u1ee2C CH\u1ea4T CH\u1ed0NG L\u00c3O H\u00d3A TO\u00c0N DI\u1ec6N"},"content":{"rendered":"<h2><span style=\"font-family: 'times new roman', times, serif;\"><strong>1. T\u1ed5ng quan NMN\u00a0<\/strong><\/span><\/h2>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN l\u00e0 vi\u1ebft t\u1eaft c\u1ee7a Nicotinamide Mononucleotide, m\u1ed9t ch\u1ea5t ti\u1ec1n ch\u1ea5t c\u1ee7a Nicotinamide Adenine Dinucleotide (NAD+). NMN \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u v\u1edbi m\u1ee5c ti\u00eau gi\u1ea3m t\u00e1c \u0111\u1ed9ng c\u1ee7a l\u00e3o h\u00f3a t\u1ebf b\u00e0o v\u00e0 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe t\u1ed5ng th\u1ec3. Trong c\u01a1 th\u1ec3, NMN tham gia v\u00e0o nhi\u1ec1u qu\u00e1 tr\u00ecnh sinh h\u1ecdc, k\u00edch th\u00edch s\u1ea3n xu\u1ea5t NAD+, m\u1ed9t coenzyme thi\u1ebft y\u1ebfu cho vi\u1ec7c s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng v\u00e0 h\u00e0ng lo\u1ea1t ph\u1ea3n \u1ee9ng sinh h\u00f3a kh\u00e1c. NMN \u0111ang \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u l\u00e0m ph\u01b0\u01a1ng ph\u00e1p ti\u1ec1m n\u0103ng \u0111\u1ec3 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng c\u01a1 b\u1ea3n c\u1ee7a c\u01a1 th\u1ec3 v\u00e0 s\u1ee9c kh\u1ecfe t\u1ebf b\u00e0o.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Nicotinamide Mononucleotide, hay NMN, l\u00e0 m\u1ed9t h\u1ee3p ch\u1ea5t sinh h\u1ecdc \u0111ang n\u1eb1m trong trung t\u00e2m c\u1ee7a nghi\u00ean c\u1ee9u khoa h\u1ecdc li\u00ean quan \u0111\u1ebfn l\u00e3o h\u00f3a v\u00e0 s\u1ee9c kh\u1ecfe t\u1ebf b\u00e0o. Trong nh\u1eefng n\u0103m g\u1ea7n \u0111\u00e2y, NMN \u0111\u00e3 tr\u1edf th\u00e0nh m\u1ed9t ch\u1ee7 \u0111\u1ec1 n\u00f3ng trong gi\u1edbi khoa h\u1ecdc v\u00e0 wellness c\u1ed9ng \u0111\u1ed3ng, nh\u1ea5t l\u00e0 sau khi nh\u1eefng nghi\u00ean c\u1ee9u ban \u0111\u1ea7u th\u1ec3 hi\u1ec7n r\u1eb1ng n\u00f3 c\u00f3 kh\u1ea3 n\u0103ng gia t\u0103ng m\u00e1u v\u00e0 c\u00e1c m\u00f4 d\u1ef1 tr\u1eef c\u1ee7a Nicotinamide Adenine Dinucleotide (NAD+), m\u1ed9t coenzyme quan tr\u1ecdng c\u00f3 trong m\u1ecdi t\u1ebf b\u00e0o s\u1ed1ng.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>T\u1ecda \u0111\u1ed9 NMN trong Qu\u00e1 Tr\u00ecnh Sinh H\u1ecdc<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">NMN l\u00e0 m\u1ed9t nucleotide xu\u1ea5t ph\u00e1t t\u1eeb ribose v\u00e0 nicotinamide. Ch\u1ee9c n\u0103ng ch\u00ednh c\u1ee7a NMN trong c\u01a1 th\u1ec3 l\u00e0 l\u00e0m ti\u1ec1n ch\u1ea5t \u0111\u1ec3 t\u1ed5ng h\u1ee3p NAD+. S\u1ef1 hi\u1ec7n di\u1ec7n c\u1ee7a NAD+ l\u00e0 c\u1ea7n thi\u1ebft \u0111\u1ec3 th\u00fac \u0111\u1ea9y hang ng\u00e0n ph\u1ea3n \u1ee9ng enzymatic, bao g\u1ed3m c\u1ea3 qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng v\u00e0 s\u1eeda ch\u1eefa DNA.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>NMN v\u00e0 Qu\u00e1 Tr\u00ecnh L\u00e3o H\u00f3a<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">Theo th\u1eddi gian, m\u1ee9c NAD+ trong c\u01a1 th\u1ec3 gi\u1ea3m \u0111i do l\u00e3o h\u00f3a v\u00e0 nguy c\u01a1 ph\u00e1t tri\u1ec3n nhi\u1ec1u b\u1ec7nh li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u0103ng cao. Nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y khi t\u0103ng c\u01b0\u1eddng NMN, m\u1ee9c NAD+ t\u0103ng l\u00ean, \u0111i\u1ec1u n\u00e0y li\u00ean quan \u0111\u1ebfn s\u1ef1 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng c\u01a1 b\u1eafp, ch\u1ee9c n\u0103ng gan, gi\u1ea3m c\u00e2n li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c, v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng th\u1ecb gi\u00e1c.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong> Hi\u1ec7u Qu\u1ea3 v\u00e0 An To\u00e0n c\u1ee7a NMN<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">Vi\u1ec7c s\u1eed d\u1ee5ng NMN nh\u01b0 m\u1ed9t ph\u1ea7n c\u1ee7a ch\u1ebf \u0111\u1ed9 b\u1ed5 sung \u0111\u00e3 tr\u1edf n\u00ean ph\u1ed5 bi\u1ebfn, v\u1edbi m\u1ee5c ti\u00eau ch\u1ed1ng l\u00e3o h\u00f3a v\u00e0 t\u0103ng c\u01b0\u1eddng s\u1ee9c kh\u1ecfe t\u1ed5ng th\u1ec3. Tuy nhi\u00ean, h\u1ea7u h\u1ebft c\u00e1c nghi\u00ean c\u1ee9u \u0111\u1ec1u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean \u0111\u1ed9ng v\u1eadt v\u00e0 nghi\u00ean c\u1ee9u tr\u00ean con ng\u01b0\u1eddi v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf. Do \u0111\u00f3, v\u1eabn c\u1ea7n nhi\u1ec1u c\u00f4ng tr\u00ecnh nghi\u00ean c\u1ee9u h\u01a1n \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh m\u1ee9c \u0111\u1ed9 hi\u1ec7u qu\u1ea3 v\u00e0 an to\u00e0n c\u1ee7a vi\u1ec7c b\u1ed5 sung NMN.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Tri\u1ec3n V\u1ecdng T\u01b0\u01a1ng Lai<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">V\u1edbi s\u1ef1 gia t\u0103ng quan t\u00e2m t\u1edbi c\u00e1c \u1ee9ng c\u1eed vi\u00ean ch\u1ed1ng l\u00e3o h\u00f3a, NMN c\u00f3 ti\u1ec1m n\u0103ng tr\u1edf th\u00e0nh m\u1ed9t ph\u1ea7n \u0111\u1eb7c bi\u1ec7t trong ti\u00eau d\u00f9ng b\u1ed5 sung \u0111\u1ec3 h\u1ed7 tr\u1ee3 tu\u1ed5i th\u1ecd v\u00e0 ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng. C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u ti\u1ebfp t\u1ee5c theo d\u00f5i ti\u1ec1m n\u0103ng c\u1ee7a NMN, li\u1ec7u ph\u00e1p ch\u1ec9nh s\u1eeda sinh h\u1ecdc m\u1ee9c \u0111\u1ed9 ph\u00e2n t\u1eed, v\u00e0 c\u00e1c \u1ee9ng d\u1ee5ng c\u00f3 th\u1ec3 trong l\u0129nh v\u1ef1c y h\u1ecdc.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Nh\u1eefng ph\u00e1t hi\u1ec7n m\u1edbi m\u1ebb v\u1ec1 NMN c\u00f3 th\u1ec3 m\u1edf \u0111\u01b0\u1eddng cho m\u1ed9t k\u1ef7 nguy\u00ean m\u1edbi c\u1ee7a s\u1ee9c kh\u1ecfe v\u00e0 tu\u1ed5i th\u1ecd, nh\u01b0ng c\u1ea7n nh\u1edb r\u1eb1ng c\u00e1c b\u01b0\u1edbc ti\u1ebfn khoa h\u1ecdc \u0111\u00f4i l\u00fac m\u1ea5t nhi\u1ec1u th\u1eddi gian v\u00e0 ki\u00ean nh\u1eabn \u0111\u1ec3 ph\u00e1t tri\u1ec3n. Trong khi \u0111\u00f3, vi\u1ec7c duy tr\u00ec l\u1ed1i s\u1ed1ng l\u00e0nh m\u1ea1nh v\u00e0 c\u00e2n \u0111\u1ed1i v\u1eabn l\u00e0 nh\u1eefng y\u1ebfu t\u1ed1 ch\u1ee7 ch\u1ed1t c\u1ee7a s\u1ee9c kh\u1ecfe t\u1ed1t v\u00e0 tu\u1ed5i th\u1ecd d\u00e0i l\u00e2u.<\/span><\/p>\n<h2><span style=\"font-family: 'times new roman', times, serif;\">2. <strong>T\u1ed5ng quan v\u1ec1 NAD+<\/strong><\/span><\/h2>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NAD+ l\u00e0 vi\u1ebft t\u1eaft c\u1ee7a Nicotinamide Adenine Dinucleotide, m\u1ed9t coenzyme quan tr\u1ecdng c\u00f3 trong m\u1ecdi t\u1ebf b\u00e0o s\u1ed1ng c\u1ee7a c\u01a1 th\u1ec3. NAD+ \u0111\u00f3ng vai tr\u00f2 then ch\u1ed1t trong nhi\u1ec1u qu\u00e1 tr\u00ecnh sinh l\u00fd quan tr\u1ecdng v\u00e0 c\u00e1c ph\u1ea3n \u1ee9ng sinh h\u00f3a m\u00e0 kh\u00f4ng c\u00f3 n\u00f3, s\u1ef1 s\u1ed1ng kh\u00f4ng th\u1ec3 t\u1ed3n t\u1ea1i. D\u01b0\u1edbi \u0111\u00e2y l\u00e0 t\u1ed5ng h\u1ee3p ki\u1ebfn th\u1ee9c v\u1ec1 NAD+:<\/span><\/p>\n<ul style=\"list-style-type: circle;\">\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ch\u1ee9c N\u0103ng C\u01a1 B\u1ea3n c\u1ee7a NAD+<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">&#8211; <strong>Chuy\u1ec3n H\u00f3a N\u0103ng L\u01b0\u1ee3ng<\/strong>: NAD+ l\u00e0 ch\u1ea5t trung gian c\u1ea7n thi\u1ebft trong qu\u00e1 tr\u00ecnh ph\u00e2n h\u1ee7y glucose, axit b\u00e9o v\u00e0 c\u00e1c ch\u1ea5t dinh d\u01b0\u1ee1ng kh\u00e1c \u0111\u1ec3 t\u1ea1o ra n\u0103ng l\u01b0\u1ee3ng ATP cho t\u1ebf b\u00e0o.<\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">&#8211; <strong>S\u1eeda Ch\u1eefa DNA<\/strong>: NAD+ gi\u00fap k\u00edch th\u00edch ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c enzyme s\u1eeda ch\u1eefa DNA, nh\u01b0 PARPs, gi\u00fap b\u1ea3o v\u1ec7 v\u00e0 ph\u1ee5c h\u1ed3i s\u1ef1 \u1ed5n \u0111\u1ecbnh c\u1ee7a DNA. <\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">&#8211; <strong>\u0110i\u1ec1u H\u00f2a S\u1ef1 Bi\u1ec3u Hi\u1ec7n Gen:<\/strong> NAD+ \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c protein g\u1ecdi l\u00e0 sirtuin, \u0111i\u1ec1u ch\u1ec9nh c\u00e1c qu\u00e1 tr\u00ecnh bi\u1ec3u hi\u1ec7n gen li\u00ean quan \u0111\u1ebfn l\u00e3o h\u00f3a v\u00e0 tu\u1ed5i th\u1ecd.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>L\u00e3o H\u00f3a v\u00e0 NAD+<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">M\u1ee9c NAD+ trong c\u01a1 th\u1ec3 gi\u1ea3m theo tu\u1ed5i t\u00e1c, g\u00e2y ra s\u1ef1 suy gi\u1ea3m ch\u1ee9c n\u0103ng mitochondrial, t\u0103ng nguy c\u01a1 m\u1eafc b\u1ec7nh li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c nh\u01b0 b\u1ec7nh tim, ti\u1ec3u \u0111\u01b0\u1eddng, v\u00e0 Alzheimer.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>T\u0103ng C\u1ea5p NAD+<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; B\u1ed5 Sung Ti\u1ec1n Ch\u1ea5t<\/strong>: S\u1eed d\u1ee5ng c\u00e1c ti\u1ec1n ch\u1ea5t nh\u01b0 nicotinamide riboside (NR) ho\u1eb7c nicotinamide mononucleotide (NMN) c\u00f3 th\u1ec3 t\u0103ng c\u1ea5p NAD+ trong c\u01a1 th\u1ec3.<\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; Ch\u1ebf \u0110\u1ed9 \u0102n:<\/strong> M\u1ed9t ch\u1ebf \u0111\u1ed9 \u0103n gi\u00e0u tryptophan v\u00e0 niacin (vitamin B3) c\u0169ng c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 s\u1ea3n xu\u1ea5t NAD+.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Nghi\u00ean C\u1ee9u V\u00e0 Ph\u00e1t Tri\u1ec3n<\/strong><\/span><br \/>\n<span style=\"font-family: 'times new roman', times, serif;\">Nghi\u00ean c\u1ee9u v\u1ec1 NAD+ ti\u1ebfp t\u1ee5c ph\u00e1t tri\u1ec3n, t\u00ecm hi\u1ec3u m\u1ed1i quan h\u1ec7 gi\u1eefa s\u1ef1 thi\u1ebfu h\u1ee5t NAD+ v\u00e0 c\u00e1c b\u1ec7nh l\u00fd c\u0169ng nh\u01b0 vi\u1ec7c kh\u00e1m ph\u00e1 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p m\u1edbi \u0111\u1ec3 t\u1ed1i \u01b0u h\u00f3a m\u1ee9c NAD+ \u0111\u1ec3 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe v\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a c\u01a1 th\u1ec3.<\/span><\/li>\n<\/ul>\n<h2><strong><span style=\"font-family: 'times new roman', times, serif;\">3. T\u00e1c d\u1ee5ng c\u1ee7a NMN<\/span><\/strong><\/h2>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN, hay nicotinamide mononucleotide, l\u00e0 m\u1ed9t ti\u1ec1n ch\u1ea5t quan tr\u1ecdng trong qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p NAD+ (nicotinamide adenine dinucleotide) trong c\u01a1 th\u1ec3 v\u00e0 mang l\u1ea1i nhi\u1ec1u t\u00e1c d\u1ee5ng ti\u1ec1m n\u0103ng \u0111\u1ed1i v\u1edbi s\u1ee9c kh\u1ecfe, bao g\u1ed3m:<\/span><\/p>\n<ul>\n<li><strong><span style=\"font-family: 'times new roman', times, serif;\">C\u1ea3i Thi\u1ec7n N\u0103ng L\u01b0\u1ee3ng T\u1ebf B\u00e0o: <\/span><\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN gi\u00fap t\u0103ng c\u1ea5p NAD+, m\u1ed9t coenzyme c\u1ea7n thi\u1ebft cho vi\u1ec7c s\u1ea3n xu\u1ea5t ATP \u2013 ngu\u1ed3n n\u0103ng l\u01b0\u1ee3ng ch\u00ednh c\u1ee7a t\u1ebf b\u00e0o<\/span><\/p>\n<ul>\n<li><strong><span style=\"font-family: 'times new roman', times, serif;\">S\u1eeda Ch\u1eefa DNA v\u00e0 T\u0103ng C\u01b0\u1eddng Mi\u1ec5n D\u1ecbch: <\/span><\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN h\u1ed7 tr\u1ee3 s\u1ef1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a c\u00e1c enzyme s\u1eeda ch\u1eefa DNA v\u00e0 c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n th\u1ec3 ch\u1ea5t mi\u1ec5n d\u1ecbch.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng ho\u1ea1t \u0111\u1ed9ng c\u1ee7a ty th\u1ec3.<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Ty th\u1ec3 l\u00e0 nh\u00e0 m\u00e1y n\u0103ng l\u01b0\u1ee3ng cho c\u01a1 th\u1ec3. Khi ty th\u1ec3 ho\u1ea1t \u0111\u1ed9ng v\u00e0 th\u1ef1c hi\u1ec7n ch\u1ee9c n\u0103ng b\u00ecnh th\u01b0\u1eddng, ch\u00fang cung c\u1ea5p \u0111\u1ee7 n\u0103ng l\u01b0\u1ee3ng cho c\u01a1 th\u1ec3. Tuy nhi\u00ean, m\u1ed7i m\u1ed9t t\u1ebf b\u00e0o c\u00f3 kho\u1ea3ng v\u00e0i ngh\u00ecn ty th\u1ec3 v\u00e0 s\u1ebd m\u1ea5t d\u1ea7n theo \u0111\u1ed9 tu\u1ed5i, g\u00e2y n\u00ean c\u00e1c b\u1ec7nh li\u00ean quan \u0111\u1ebfn ty th\u1ec3, trong \u0111\u00f3 c\u00f3 ung th\u01b0. B\u1ec7nh l\u00fd do ty th\u1ec3 th\u01b0\u1eddng l\u00e0 b\u1ec7nh do m\u1ed9t qu\u00e1 tr\u00ecnh l\u00e2u d\u00e0i t\u00edch l\u0169y ho\u1eb7c c\u00f3 y\u1ebfu t\u1ed1 di truy\u1ec1n.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">B\u1ed5 sung NMN l\u00e0m tr\u1ebb h\u00f3a ty th\u1ec3 trong m\u1ecdi t\u1ebf b\u00e0o trong c\u01a1 th\u1ec3, gi\u00fap c\u00e1c ty th\u1ec3 ho\u1ea1t \u0111\u1ed9ng b\u00ecnh th\u01b0\u1eddng, ng\u0103n ng\u1eeba h\u00ecnh th\u00e0nh kh\u1ed1i u, x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch v\u00e0 nhi\u1ec1u b\u1ec7nh l\u00e3o h\u00f3a.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>K\u00edch ho\u1ea1t gen TR\u01af\u1edcNG TH\u1ecc Sirtuins: k\u00edch ho\u1ea1t 7 gen sirtuin\u00a0<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">C\u01a1 th\u1ec3 con ng\u01b0\u1eddi ch\u1ee9a kho\u1ea3ng 25.000 gen chi\u1ebfm kho\u1ea3ng 3 t\u1ef7 ch\u1eef (c\u1eb7p base) c\u1ee7a DNA. V\u1edbi s\u1ed1 l\u01b0\u1ee3ng kh\u1ed5ng l\u1ed3 nh\u01b0 v\u1eady, kh\u00f4ng ph\u1ea3i gen n\u00e0o c\u0169ng \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t. Trong s\u1ed1 \u0111\u00f3 c\u00f3 Gen Sirtuins \u2013 lo\u1ea1i gen chi\u1ebfm m\u1ed9t l\u01b0\u1ee3ng r\u1ea5t nh\u1ecf trong DNA nh\u01b0ng l\u1ea1i chi\u1ebfm vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c k\u00e9o d\u00e0i tu\u1ed5i th\u1ecd c\u1ee7a con ng\u01b0\u1eddi. Theo c\u00e1c nghi\u00ean c\u1ee9u t\u1ea1i Nh\u1eadt B\u1ea3n, Gen Sirtuins \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y \u1edf nh\u1eefng ng\u01b0\u1eddi c\u00f3 tu\u1ed5i th\u1ecd h\u01a1n 100 tu\u1ed5i.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Gen tr\u01b0\u1eddng th\u1ecd Sirtuins l\u00e0 m\u1ed9t nh\u00f3m c\u00e1c protein c\u00f3 t\u00e1c \u0111\u1ed9ng r\u1ed9ng l\u1edbn \u0111\u1ebfn ch\u1ee9c n\u0103ng c\u1ee7a c\u01a1 th\u1ec3, bao g\u1ed3m tu\u1ed5i th\u1ecd, ch\u1ed1ng l\u00e3o h\u00f3a, v\u00e0 s\u1ee9c kh\u1ecfe t\u1ebf b\u00e0o. C\u00e1c gen Sirtuins \u0111\u01b0\u1ee3c m\u00e3 h\u00f3a cho c\u00e1c protein n\u00e0y v\u00e0 ch\u00fang \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn v\u1edbi kh\u1ea3 n\u0103ng t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a th\u00f4ng qua nhi\u1ec1u c\u01a1 ch\u1ebf:<\/span><\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul style=\"list-style-type: circle;\">\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>\u0110i\u1ec1u Ti\u1ebft Qu\u00e1 Tr\u00ecnh Chuy\u1ec3n H\u00f3a N\u0103ng L\u01b0\u1ee3ng:<\/strong> Sirtuins gi\u00fap \u0111i\u1ec1u ch\u1ec9nh qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a v\u00e0 s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng trong c\u01a1 th\u1ec3, t\u1eeb \u0111\u00f3 gi\u00fap duy tr\u00ec t\u00ednh \u1ed5n \u0111\u1ecbnh v\u00e0 ch\u1ee9c n\u0103ng hi\u1ec7u qu\u1ea3 c\u1ee7a c\u00e1c t\u1ebf b\u00e0o, \u0111\u1eb7c bi\u1ec7t l\u00e0 trong c\u01a1 h\u1ecdc v\u00e0 n\u00e3o b\u1ed9.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>S\u1eeda Ch\u1eefa DNA:<\/strong> C\u00e1c protein n\u00e0y \u0111\u00f3ng vai tr\u00f2 trong vi\u1ec7c s\u1eeda ch\u1eefa DNA b\u1ecb h\u1ecfng v\u00e0 b\u1ea3o v\u1ec7 v\u1eadt li\u1ec7u di truy\u1ec1n kh\u1ecfi c\u00e1c t\u00e1c \u0111\u1ed9ng ti\u00eau c\u1ef1c t\u1eeb m\u00f4i tr\u01b0\u1eddng.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ch\u1ed1ng Stress Oxy H\u00f3a:<\/strong> Sirtuins \u0111\u01b0\u1ee3c cho l\u00e0 c\u00f3 kh\u1ea3 n\u0103ng t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng ch\u1ed1ng l\u1ea1i stress oxy h\u00f3a, gi\u00fap gi\u1ea3m thi\u1ec3u t\u1ed5n th\u01b0\u01a1ng t\u1ebf b\u00e0o v\u00e0 t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng ph\u1ee5c h\u1ed3i.<\/span><\/li>\n<li><span style=\"font-family: 'times new roman', times, serif;\">\u00a0<strong>Qu\u00e1 tr\u00ecnh Vi\u00eam v\u00e0 L\u00e3o h\u00f3a:<\/strong> Sirtuins c\u00f3 li\u00ean quan \u0111\u1ebfn vi\u1ec7c gi\u1ea3m vi\u00eam, qu\u00e1 tr\u00ecnh \u0111\u01b0\u1ee3c xem l\u00e0 nguy\u00ean nh\u00e2n c\u1ee7a nhi\u1ec1u b\u1ec7nh li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c v\u00e0 l\u00e3o h\u00f3a.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Nh\u1edd kh\u1ea3 n\u0103ng t\u0103ng sinh Coenzyme NAD+, y\u1ebfu t\u1ed1 quan tr\u1ecdng \u0111\u1ec3 k\u00edch ho\u1ea1t Gen Sirtuins, Gen Sirtuins s\u1eeda ch\u1eefa DNA h\u01b0 t\u1ed5n, ng\u0103n ng\u1eeba h\u01a1n 100 nguy\u00ean nh\u00e2n g\u00e2y l\u00e3o h\u00f3a. N\u0103m 2017, t\u1ea1p ch\u00ed Science \u0111\u0103ng t\u1ea3i th\u00ed nghi\u1ec7m c\u1ee7a Ti\u1ebfn s\u1ef9 David Sinclair (\u0111\u1ea1i h\u1ecdc Y Harvard) v\u1edbi vi\u1ec7c b\u1ed5 sung ho\u1ea1t ch\u1ea5t NMN \u0111\u1ec3 k\u00edch ho\u1ea1t gen Sirtuins tr\u00ean nh\u1eefng con chu\u1ed9t 20 th\u00e1ng tu\u1ed5i (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng con ng\u01b0\u1eddi \u1edf tu\u1ed5i 60-70). K\u1ebft qu\u1ea3 cho th\u1ea5y c\u00e1c ch\u1ec9 s\u1ed1 c\u01a1 th\u1ec3 c\u1ee7a chu\u1ed9t \u0111\u01b0\u1ee3c kh\u00f4i ph\u1ee5c v\u1ec1 tr\u1ea1ng th\u00e1i c\u1ee7a ch\u00fang khi c\u00f2n tr\u1ebb (t\u01b0\u01a1ng \u0111\u01b0\u01a1ng t\u00ecnh tr\u1ea1ng con ng\u01b0\u1eddi 30 tu\u1ed5i).<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>S\u1eeda ch\u1eefa DNA b\u1ecb t\u1ed5n th\u01b0\u01a1ng<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NAD+ cung c\u1ea5p n\u0103ng l\u01b0\u1ee3ng qua \u0111\u00f3 th\u00fac \u0111\u1ea9y s\u1ef1 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a Gen tr\u01b0\u1eddng th\u1ecd Sirtuin. S\u1ef1 gia t\u0103ng c\u1ee7a Gen tr\u01b0\u1eddng th\u1ecd Sirtuin trong chu\u1ed7i chu tr\u00ecnh c\u1ee7a NAD+ gi\u00fap tr\u1ebb h\u00f3a, s\u1eeda ch\u1eefa t\u1ebf b\u00e0o, h\u1ed7 tr\u1ee3 gi\u00fap chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng, \u0111\u1ea3m b\u1ea3o ch\u1ee9c n\u0103ng c\u1ee7a c\u00e1c gene ph\u00f2ng v\u1ec7, b\u1ea3o v\u1ec7 c\u01a1 th\u1ec3 kh\u1ecfi s\u1ef1 l\u00e3o h\u00f3a, b\u1ec7nh t\u1eadt.\u00a0NMN c\u0169ng s\u1eeda ch\u1eefa c\u00e1c t\u1ed5n th\u01b0\u01a1ng DNA do b\u1ee9c x\u1ea1 v\u00e0 tu\u1ed5i gi\u00e0.<\/span><\/p>\n<ul>\n<li><strong><span style=\"font-family: 'times new roman', times, serif;\"> Ch\u1ed1ng L\u00e3o H\u00f3a: <\/span><\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN c\u00f3 th\u1ec3 g\u00f3p ph\u1ea7n trong vi\u1ec7c gi\u1ea3m t\u00e1c \u0111\u1ed9ng c\u1ee7a l\u00e3o h\u00f3a t\u1ea1i c\u1ea5p \u0111\u1ed9 t\u1ebf b\u00e0o, gi\u00fap duy tr\u00ec s\u1ee9c kh\u1ecfe v\u00e0 ch\u1ee9c n\u0103ng c\u1ee7a c\u00e1c c\u01a1 quan.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>T\u0103ng c\u01b0\u1eddng ch\u1ee9c n\u0103ng n\u00e3o b\u1ed9, <\/strong><\/span><strong style=\"font-family: 'times new roman', times, serif; font-size: 16px;\">C\u1ea3i thi\u1ec7n tr\u00ed nh\u1edb, tinh th\u1ea7n<\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">M\u1ed9t trong nh\u1eefng c\u0103n b\u1ec7nh li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c t\u00e0n kh\u1ed1c nh\u1ea5t ch\u00ednh l\u00e0 b\u1ec7nh Alzheimer. C\u00e1c m\u1ea1ch m\u00e1u tr\u1edf n\u00ean r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng khi gi\u00e0 \u0111i, l\u01b0u l\u01b0\u1ee3ng m\u00e1u \u0111\u1ebfn n\u00e3o b\u1ecb suy gi\u1ea3m, d\u1eabn \u0111\u1ebfn suy gi\u1ea3m nh\u1eadn th\u1ee9c.\u00a0<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN gi\u00fap l\u00e0m t\u0103ng l\u01b0u l\u01b0\u1ee3ng m\u00e1u \u0111\u1ebfn n\u00e3o v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng nh\u1eadn th\u1ee9c,\u00a0 l\u00e0m ch\u1eadm s\u1ef1 kh\u1edfi ph\u00e1t \u0111\u1ed9t qu\u1ef5, ng\u0103n ng\u1eeba t\u1ed5n th\u01b0\u01a1ng do \u0111\u1ed9t qu\u1ef5, c\u1ea3i thi\u1ec7n nh\u1eadn th\u1ee9c v\u00e0 s\u1ee9c kh\u1ecfe c\u1ee7a c\u01a1 th\u1ec3 sau \u0111\u1ed9t qu\u1ef5.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Nghi\u00ean c\u1ee9u c\u1ee7a c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1eeb \u0110\u1ea1i h\u1ecdc Oklahoma (Hoa K\u1ef3) \u0111\u0103ng tr\u00ean t\u1ea1p ch\u00ed GeoScience cho th\u1ea5y r\u1eb1ng vi\u1ec7c b\u1ed5 sung NMN gi\u00fap \u0111\u1ea3o ng\u01b0\u1ee3c t\u00e1c \u0111\u1ed9ng c\u1ee7a l\u00e3o h\u00f3a l\u00ean c\u00e1c neuron th\u1ea7n kinh. T\u1eeb \u0111\u00f3 ng\u0103n ng\u1eeba r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng n\u00e3o v\u00e0 t\u1ebf b\u00e0o N\u01a1ron th\u1ea7n kinh.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN c\u0169ng ho\u1ea1t \u0111\u1ed9ng tr\u00ean n\u00e3o, c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng c\u1ee7a h\u1ec7 th\u1ed1ng th\u1ea7n kinh t\u1ef1 tr\u1ecb \u0111\u1ec3 c\u00e2n b\u1eb1ng c\u01a1 th\u1ec3 gi\u00e0 v\u00e0 c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng b\u00ecnh th\u01b0\u1eddng c\u1ee7a n\u00f3. Melatonin, \u0111\u01b0\u1ee3c t\u0103ng l\u00ean do t\u00e1c \u0111\u1ed9ng c\u1ee7a th\u00e2n n\u00e3o gi\u00fap c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng bu\u1ed3n ng\u1ee7.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">\u00a0Trong m\u1ed9t nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n t\u1ea1i Nh\u1eadt b\u1ea3n v\u1edbi ng\u01b0\u1eddi cao tu\u1ed5i tr\u00ean 65 tu\u1ed5i, s\u1eed d\u1ee5ng 250mg NMN trong 12 tu\u1ea7n. M\u1eb7c d\u00f9 NMN kh\u00f4ng c\u1ea3i thi\u1ec7n v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng gi\u1ea5c ng\u1ee7 nh\u01b0ng n\u00f3 c\u00f3 t\u00e1c d\u1ee5ng c\u1ea3i thi\u1ec7n t\u00ecnh tr\u1ea1ng bu\u1ed3n ng\u1ee7. Nh\u1eefng ng\u01b0\u1eddi tham gia nghi\u00ean c\u1ee9u th\u00f4ng b\u00e1o c\u1ea3m gi\u00e1c d\u1ec5 \u0111i v\u00e0o gi\u1ea5c ng\u1ee7 h\u01a1n khi b\u1ed5 sung NMN.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ph\u1ee5c h\u1ed3i s\u1ee9c kh\u1ecfe m\u1ea1ch m\u00e1u,\u00a0<\/strong><\/span><strong style=\"font-family: 'times new roman', times, serif; font-size: 16px;\">C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng c\u01a1, da.<\/strong><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">C\u00e1c m\u1ea1ch m\u00e1u gi\u00fap v\u1eadn chuy\u1ec3n c\u00e1c ch\u1ea5t dinh d\u01b0\u1ee1ng \u0111\u1ebfn t\u1eebng t\u1ebf b\u00e0o. Theo th\u1eddi gian, h\u1ec7 th\u1ed1ng tu\u1ea7n ho\u00e0n m\u00e1u s\u1ebd suy gi\u1ea3m c\u00e1c m\u1ea1ch m\u00e1u c\u1ee7a ch\u00fang ta tr\u1edf n\u00ean c\u1ee9ng v\u00e0 d\u1ec5 b\u1ecb t\u1eafc ngh\u1ebdn h\u01a1n, nguy c\u01a1 d\u1eabn \u0111\u1ebfn \u0111au tim ho\u1eb7c \u0111\u1ed9t qu\u1ef5.\u00a0<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 th\u1ec3 \u0111\u1ea3o ng\u01b0\u1ee3c qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a m\u1ea1ch m\u00e1u b\u1eb1ng c\u00e1ch kh\u00f4i ph\u1ee5c \u0111\u1ed9 \u0111\u00e0n h\u1ed3i c\u1ee7a m\u1ea1ch m\u00e1u, h\u1ed7 tr\u1ee3 t\u0103ng c\u01b0\u1eddng l\u01b0u th\u00f4ng m\u00e1u, ng\u0103n ch\u1eb7n nh\u1eefng b\u1ec7nh v\u1ec1 tim m\u1ea1ch, b\u1ea3o v\u1ec7 v\u00e0 c\u1ea3i thi\u1ec7n c\u00e1c ch\u1ee9c n\u0103ng c\u1ee7a tim.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Con ng\u01b0\u1eddi d\u1ef1a v\u00e0o c\u01a1 x\u01b0\u01a1ng \u0111\u1ec3 di chuy\u1ec3n, sinh ho\u1ea1t v\u00e0 t\u0103ng c\u01b0\u1eddng s\u1ee9c m\u1ea1nh. Theo th\u1eddi gian, c\u01a1 b\u1eafp m\u1ea5t kh\u1ea3 n\u0103ng t\u00e1i t\u1ea1o v\u00e0 ph\u00e1t tri\u1ec3n, d\u1eabn \u0111\u1ebfn s\u1ef1 suy gi\u1ea3m s\u1ee9c m\u1ea1nh v\u00e0 k\u00edch th\u01b0\u1edbc c\u01a1 khi\u1ebfn c\u01a1 th\u1ec3 m\u1ec7t m\u1ecfi v\u00e0 s\u1ee9c ch\u1ecbu \u0111\u1ef1ng th\u1ec3 ch\u1ea5t k\u00e9m h\u01a1n.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">\u00a0M\u1ed9t nghi\u00ean c\u1ee9u \u0111\u00e3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u00ean 48 v\u1eadn \u0111\u1ed9ng vi\u00ean ch\u1ea1y nghi\u1ec7p d\u01b0 u\u1ed1ng NMN \u1edf c\u00e1c m\u1ee9c li\u1ec1u kh\u00e1c nhau 300, 600, 1200mg trong 6 tu\u1ea7n. Cu\u1ed1i nghi\u00ean c\u1ee9u nh\u1eefng ng\u01b0\u1eddi b\u1ed5 sung NMN cho th\u1ea5y gi\u1ea3m m\u1ee9c \u0111\u1ed9 m\u1ecfi c\u01a1 b\u1eafp h\u01a1n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi s\u1eed d\u1ee5ng gi\u1ea3 d\u01b0\u1ee3c.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">B\u1ed5 sung NMN l\u00e0m t\u0103ng s\u1ee9c m\u1ea1nh v\u00e0 s\u1ee9c b\u1ec1n th\u1ec3 ch\u1ea5t, c\u1ea3i thi\u1ec7n s\u1ee9c m\u1ea1nh v\u00e0 hi\u1ec7u su\u1ea5t c\u01a1 b\u1eafp. Nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u1edf nam gi\u1edbi l\u1edbn tu\u1ed5i u\u1ed1ng NMN trong v\u00f2ng 8 tu\u1ea7n, cho th\u1ea5y u\u1ed1ng NMN l\u00e0m t\u0103ng m\u1ee9c NAD+ v\u00e0 m\u1ed9t ti\u1ec1n ch\u1ea5t NAD+ kh\u00e1c \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 nicotinamide riboside (NR) g\u00f3p ph\u1ea7n c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 v\u1ec1 c\u00e1c ch\u1ec9 s\u1ed1 v\u1ec1 s\u1ee9c m\u1ea1nh c\u01a1 b\u1eafp.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">L\u00e3o h\u00f3a l\u00e0 m\u1ed9t qu\u00e1 tr\u00ecnh ph\u1ee9c t\u1ea1p c\u00f3 li\u00ean quan \u0111\u1ebfn gene, DNA, bi\u1ebfn \u0111\u1ed5i ngo\u1ea1i di truy\u1ec1n, r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng ty th\u1ec3\u2026n\u00ean v\u1edbi nh\u1eefng ch\u1ea5t ch\u1ed1ng oxy h\u00f3a nh\u01b0 Vitamin C, Vitamin E, vitamin B, coenzyme Q10, axit lipoic, canxi, axit b\u00e9o omega-3, k\u1ebdm\u2026 ch\u01b0a \u0111\u1ee7 \u0111\u1ec3 tr\u1ebb h\u00f3a l\u00e0n da.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN ch\u1ed1ng l\u00e3o h\u00f3a b\u1eb1ng c\u00e1ch \u0111\u1ea9y nhanh qu\u00e1 tr\u00ecnh thay da t\u1ef1 nhi\u00ean c\u1ee7a c\u01a1 th\u1ec3, t\u00e1i sinh Collagen v\u00e0 Elastin gi\u00fap cho da c\u0103ng m\u1ecbn, s\u1eeda ch\u1eefa t\u1ed5n th\u01b0\u01a1ng tr\u00ean da b\u1eb1ng c\u00e1ch s\u1eeda ch\u1eefa DNA h\u01b0 t\u1ed5n. K\u00edch th\u00edch l\u01b0u th\u00f4ng v\u00e0 tr\u1ebb h\u00f3a m\u1ea1ch m\u00e1u, c\u00e1i thi\u1ec7n s\u1eafc da, s\u1ef1 t\u01b0\u01a1i t\u1eafn c\u1ee7a l\u00e0n da v\u00e0 c\u1ea3i thi\u1ec7n r\u00f5 r\u1ec7t c\u00e1c d\u1ea5u hi\u1ec7u l\u00e3o h\u00f3a l\u00e0n da gi\u00fap ng\u0103n ch\u1eb7n n\u1ebfp nh\u0103n, ch\u1ea3y x\u1ec7 tr\u00ean da. \u0110\u1ed3ng th\u1eddi gi\u1ea3m t\u00e1c \u0111\u1ed9ng x\u1ea5u c\u1ee7a tia UV, tia b\u1ee9c x\u1ea1 gi\u00fap l\u00e0n da kh\u1ecfe m\u1ea1nh.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Th\u00fac \u0111\u1ea9y tr\u00e1i tim kh\u1ecfe m\u1ea1nh<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN gi\u00fap c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe tim m\u1ea1ch th\u00f4ng qua vi\u1ec7c t\u0103ng c\u01b0\u1eddng s\u1ee9c kh\u1ecfe c\u1ee7a c\u00e1c t\u1ebf b\u00e0o trong c\u01a1 tim v\u00e0 gi\u1ea3m vi\u00eam, c\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim m\u1ea1ch th\u00f4ng qua m\u1ed9t s\u1ed1 c\u01a1 ch\u1ebf sinh h\u1ecdc kh\u00e1c nhau:<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\">&#8211; <strong>T\u0103ng c\u1ea5p NAD+<\/strong>: NMN l\u00e0 ti\u1ec1n ch\u1ea5t c\u1ee7a NAD+, m\u1ed9t coenzyme c\u1ea7n thi\u1ebft cho c\u00e1c ph\u1ea3n \u1ee9ng sinh l\u00fd, bao g\u1ed3m qu\u00e1 tr\u00ecnh s\u1ea3n sinh ATP, ngu\u1ed3n n\u0103ng l\u01b0\u1ee3ng ch\u00ednh cho c\u00e1c t\u1ebf b\u00e0o bao g\u1ed3m c\u1ea3 t\u1ebf b\u00e0o c\u01a1 tim. M\u1ee9c NAD+ t\u0103ng l\u00ean c\u00f3 th\u1ec3 gi\u00fap t\u1ebf b\u00e0o c\u01a1 tim ho\u1ea1t \u0111\u1ed9ng hi\u1ec7u qu\u1ea3 h\u01a1n.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; C\u1ea3i Thi\u1ec7n Ch\u1ee9c N\u0103ng Ti Th\u1ec3<\/strong>: Ti th\u1ec3 trong t\u1ebf b\u00e0o c\u01a1 tim c\u00f3 nhi\u1ec7m v\u1ee5 s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng. NMN c\u00f3 th\u1ec3 gi\u00fap c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe v\u00e0 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a mitochondria, t\u1eeb \u0111\u00f3 n\u00e2ng cao kh\u1ea3 n\u0103ng s\u1ea3n sinh n\u0103ng l\u01b0\u1ee3ng trong c\u01a1 tim.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; Ch\u1ed1ng Vi\u00eam:<\/strong> NMN c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng vi\u00eam, l\u00e0m gi\u1ea3m t\u00ecnh tr\u1ea1ng vi\u00eam v\u00e0 stress oxy h\u00f3a c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng x\u1ea5u \u0111\u1ebfn tim m\u1ea1ch.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; T\u1ed1i \u01afu H\u00f3a M\u1ea1ch M\u00e1u:<\/strong> NMN c\u00f3 th\u1ec3 h\u1ed7 tr\u1ee3 ch\u1ee9c n\u0103ng endothelial c\u1ee7a m\u1ea1ch m\u00e1u, c\u1ea3i thi\u1ec7n s\u1ef1 l\u01b0u th\u00f4ng m\u00e1u v\u00e0 gi\u1ea3m nguy c\u01a1 v\u1ec1 c\u00e1c v\u1ea5n \u0111\u1ec1 tim m\u1ea1ch nh\u01b0 huy\u1ebft \u00e1p cao v\u00e0 x\u01a1 v\u1eefa \u0111\u1ed9ng m\u1ea1ch.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>&#8211; T\u00e1c d\u1ee5ng l\u00ean c\u00e1c Sirtuin:<\/strong> NMN t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn c\u00e1c sirtuin, m\u1ed9t nh\u00f3m protein gi\u00fap \u0111i\u1ec1u ch\u1ec9nh c\u0103ng th\u1eb3ng v\u00e0 tu\u1ed5i th\u1ecd t\u1ebf b\u00e0o. C\u00e1c sirtuin n\u00e0y c\u00f3 th\u1ec3 c\u00f3 t\u00e1c \u0111\u1ed9ng t\u00edch c\u1ef1c \u0111\u1ebfn s\u1ee9c kh\u1ecfe tim m\u1ea1ch.<\/span><\/p>\n<p><strong><span style=\"font-family: 'times new roman', times, serif;\">\u00a0NMN b\u1ea3o v\u1ec7 tim kh\u1ecfi t\u1ed5n th\u01b0\u01a1ng nh\u1edd vi\u1ec7c s\u1eeda ch\u1eefa DNA v\u00e0 th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh t\u00e1i t\u1ea1o v\u00e0 duy tr\u00ec \u0111\u1ed9 \u0111\u00e0n h\u1ed3i c\u1ee7a m\u1ea1ch m\u00e1u, ng\u0103n ng\u1eeba thi\u1ebfu m\u00e1u c\u1ee5c b\u1ed9 v\u00e0 huy\u1ebft kh\u1ed1i. C\u1ea3i thi\u1ec7n ch\u1ee9c n\u0103ng tim, ng\u0103n ng\u1eeba r\u1ed1i lo\u1ea1n nh\u1ecbp tim v\u00e0 ki\u1ec3m so\u00e1t c\u00e1c y\u1ebfu t\u1ed1 g\u00e2y \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn tim nh\u01b0 huy\u1ebft \u00e1p, ti\u1ec3u \u0111\u01b0\u1eddng, m\u00e1u nhi\u1ec5m m\u1ee1\u2026<\/span><\/strong><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>H\u1ed7 tr\u1ee3 trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">N\u1ed3ng \u0111\u1ed9 NAD t\u0103ng cao c\u00f3 th\u1ec3 gi\u00fap b\u1ea3o v\u1ec7 t\u1ebf b\u00e0o ch\u1ed1ng l\u1ea1i stress oxy h\u00f3a v\u00e0 t\u1ed5n th\u01b0\u01a1ng DNA. Nghi\u00ean c\u1ee9u t\u00e1c d\u1ee5ng b\u1ed5 sung NMN C\u00e1c nghi\u00ean c\u1ee9u tr\u00ean m\u00f4 h\u00ecnh \u0111\u1ed9ng v\u1eadt, \u0111\u1eb7c bi\u1ec7t l\u00e0 chu\u1ed9t, cho th\u1ea5y r\u1eb1ng ch\u1ea5t b\u1ed5 sung NMN c\u00f3 th\u1ec3 mang l\u1ea1i nhi\u1ec1u l\u1ee3i \u00edch kh\u00e1c nhau, bao g\u1ed3m \u0111\u1ea3o ng\u01b0\u1ee3c qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a v\u00e0 c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe nh\u1eadn th\u1ee9c.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Nghi\u00ean c\u1ee9u cho th\u1ea5y NMN l\u00e0m t\u0103ng t\u1ebf b\u00e0o CAR-T &#8211; t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch ch\u1ed1ng kh\u1ed1i u &#8211; t\u0103ng sinh l\u00ean \u0111\u1ebfn 180 l\u1ea7n, \u0111\u1ed3ng th\u1eddi k\u00e9o d\u00e0i kh\u1ea3 n\u0103ng ti\u00eau di\u1ec7t t\u1ebf b\u00e0o ung th\u01b0 c\u1ee7a t\u1ebf b\u00e0o.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ng\u0103n ng\u1eeba v\u00e0 ph\u00f2ng ch\u1ed1ng \u0111\u1ed9t qu\u1ef5<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">C\u00e1c chuy\u00ean gia s\u1ee9c kh\u1ecfe \u0111\u00e3 ch\u1ee9ng minh NMN ch\u1ee9a Nicotinamide Mononucleotide c\u00f3 kh\u1ea3 n\u0103ng ph\u00f2ng tr\u00e1nh \u0111\u1ed9t qu\u1ef5 hi\u1ec7u qu\u1ea3. Ho\u1ea1t ch\u1ea5t NAD+ trong n\u00e3o \u0111\u01b0\u1ee3c s\u1ea3n sinh k\u00edch ho\u1ea1t sirtuins ch\u1ed1ng l\u00e3o h\u00f3a. Ngo\u00e0i ra c\u00f2n \u0111\u1ea9y l\u00f9i c\u00e1c c\u0103n b\u1ec7nh nh\u01b0 tho\u00e1i h\u00f3a th\u1ea7n kinh, ti\u1ec3u \u0111\u01b0\u1eddng, tim m\u1ea1ch, suy gi\u1ea3m h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ch\u1ed1ng l\u1ea1i b\u1ec7nh b\u00e9o ph\u00ec v\u00e0 b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn s\u1ef1 chuy\u1ec3n h\u00f3a c\u1ee7a m\u00f4 m\u1ee1, k\u00edch th\u00edch \u0111\u1ed1t ch\u00e1y ch\u1ea5t b\u00e9o t\u00edch t\u1ee5 trong c\u01a1 th\u1ec3, gi\u00fap ch\u00fang ta c\u00f3 v\u00f3c d\u00e1ng \u0111\u1eb9p h\u01a1n.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">B\u1ec7nh b\u00e9o ph\u00ec c\u00f3 li\u00ean quan \u0111\u1ebfn m\u1ed9t lo\u1ea1t c\u00e1c thi\u1ebfu h\u1ee5t trao \u0111\u1ed5i ch\u1ea5t, bao g\u1ed3m kh\u00e1ng insulin c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng. NMN l\u00e0m t\u0103ng g\u1ea5p \u0111\u00f4i s\u1ed1 l\u01b0\u1ee3ng ty th\u1ec3- \u0111\u00f3ng v\u00e0i tr\u00f2 th\u00fac \u0111\u1ea9y chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng, k\u00edch th\u00edch ph\u00e2n h\u1ee7y ch\u1ea5t b\u00e9o gi\u00fap nh\u1eefng ng\u01b0\u1eddi b\u00e9o ph\u00ec gi\u1ea3m m\u1ee1.\u00a0Kh\u00f4ng nh\u1eefng th\u1ebf, NMN c\u0169ng h\u1ed7 tr\u1ee3 c\u00e1c enzyme, h\u1ed7 tr\u1ee3 t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t n\u0103ng l\u01b0\u1ee3ng t\u1eeb carbohydrate v\u00e0 protein.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u1ea3i thi\u1ec7n \u0111\u1ed9 nh\u1ea1y insulin c\u1ee7a c\u01a1 \u1edf ph\u1ee5 n\u1eef l\u1edbn tu\u1ed5i (<em>m\u1ed9t nghi\u00ean c\u1ee9u v\u1edbi <\/em><em>10 ph\u1ee5 n\u1eef tu\u1ed5i m\u00e3n kinh, th\u1eeba c\u00e2n v\u00e0 m\u1eafc ti\u1ec3u \u0111\u01b0\u1eddng tuyp II b\u1ed5 sung 250mg NMN trong m\u01b0\u1eddi tu\u1ea7n. K\u1ebft qu\u1ea3 cho th\u1ea5y NMN l\u00e0m t\u0103ng \u0111\u1ed9 nh\u1ea1y c\u1ea3m insulin).<\/em> Do \u0111\u00f3, trong khi \u0111i\u1ec1u ch\u1ec9nh l\u1ed1i s\u1ed1ng sinh ho\u1ea1t nh\u01b0 t\u1eadp th\u1ec3 d\u1ee5c k\u1ebft h\u1ee3p ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng l\u00e0nh m\u1ea1nh vi\u1ec7c c\u1ea7n thi\u1ebft ph\u1ea3i b\u1ed5 sung Vitamin B3 \u2013 nguy\u00ean li\u1ec7u th\u00f4 c\u1ee7a NMN, l\u00e0 ch\u1ea5t dinh d\u01b0\u1ee1ng c\u1ea7n thi\u1ebft cho qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p Insulin v\u00e0 l\u00e0 y\u1ebfu t\u1ed1 duy nh\u1ea5t gi\u00fap gi\u1ea3m l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u. \u0110\u1ed3ng th\u1eddi, k\u00edch ho\u1ea1t Gen Sirtuins ho\u1ea1t \u0111\u1ed9ng c\u0169ng l\u00e0 y\u1ebfu t\u1ed1 quan tr\u1ecdng \u0111\u1ec3 ng\u0103n ng\u1eeba s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ti\u1ec3u \u0111\u01b0\u1eddng.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>T\u0103ng c\u01b0\u1eddng s\u1ee9c kh\u1ecfe n\u1ed9i t\u1ea1ng<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Ngo\u00e0i vi\u1ec7c l\u00e0m ch\u1eadm l\u00e3o h\u00f3a c\u1ee7a n\u00e3o, m\u1ea1ch m\u00e1u, c\u01a1, tim, trao \u0111\u1ed5i ch\u1ea5t v\u00e0 m\u1eaft, NMN c\u00f2n \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 l\u00e0m tr\u1ebb h\u00f3a c\u00e1c t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a x\u01b0\u01a1ng v\u00e0 th\u00fac \u0111\u1ea9y qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh x\u01b0\u01a1ng. NMN c\u0169ng \u0111\u1ea3o ng\u01b0\u1ee3c qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a \u0111\u01b0\u1eddng ru\u1ed9t, b\u1ea3o v\u1ec7 ch\u1ed1ng l\u1ea1i s\u1ef1 suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn do tu\u1ed5i t\u00e1c v\u00e0 \u1ee9c ch\u1ebf s\u1ef1 kh\u1edfi ph\u00e1t c\u1ee7a x\u01a1 h\u00f3a gan.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>Tr\u1ebb h\u00f3a sinh l\u00fd cho c\u1ea3 nam v\u00e0 n\u1eef gi\u1edbi<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Ti\u1ebfn s\u0129 Thomas A. Purula c\u1ee7a \u0110\u1ea1i h\u1ecdc Wisconsin \u1edf Hoa K\u1ef3 \u0111\u00e3 c\u00f4ng b\u1ed1 m\u1ed9t nghi\u00ean c\u1ee9u tr\u00ean t\u1ea1p ch\u00ed khoa h\u1ecdc Hoa K\u1ef3 Science. Theo k\u1ebft qu\u1ea3, ng\u01b0\u1eddi ta th\u1ea5y r\u1eb1ng ED (r\u1ed1i lo\u1ea1n c\u01b0\u01a1ng d\u01b0\u01a1ng) v\u00e0 h\u00f3i \u0111\u1ea7u, th\u01b0\u1eddng \u0111\u01b0\u1ee3c coi l\u00e0 lo l\u1eafng c\u1ee7a \u0111\u00e0n \u00f4ng, c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n b\u1eb1ng c\u00e1ch k\u00edch ho\u1ea1t gen sirtuin qua NMN.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN c\u0169ng t\u0103ng kh\u1ea3 n\u0103ng s\u1ed1ng v\u00e0 sinh s\u1ea3n c\u1ee7a t\u1ebf b\u00e0o tr\u1ee9ng, gi\u00fap gi\u1ea3m thi\u1ec3u c\u00e1c t\u1ed5n th\u01b0\u01a1ng v\u00e0 tr\u1ebb h\u00f3a ch\u1ea5t l\u01b0\u1ee3ng tr\u1ee9ng. Kh\u00f4ng nh\u1eefng th\u1ebf, b\u1ed5 sung NMN c\u00f2n gi\u00fap ph\u1ee5c h\u1ed3i kh\u1ea3 n\u0103ng sinh s\u1ea3n c\u1ee7a ph\u1ee5 n\u1eef c\u00f3 tu\u1ed5i v\u00e0 t\u0103ng c\u01b0\u1eddng kh\u1ea3 n\u0103ng li\u00ean k\u1ebft c\u1ee7a tr\u1ee9ng v\u1edbi tinh tr\u00f9ng, gi\u00fap qu\u00e1 tr\u00ecnh th\u1ee5 tinh d\u1ec5 x\u1ea3y ra h\u01a1n.<\/span><\/p>\n<ul>\n<li><span style=\"font-family: 'times new roman', times, serif;\"><strong>L\u00e0m gi\u1ea3m tri\u1ec7u ch\u1ee9ng h\u1eadu Covid<\/strong><\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: 'times new roman', times, serif;\">T\u1ebf b\u00e0o s\u1eed d\u1ee5ng NAD+ trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng l\u1ea1i corona virus, khi\u1ebfn l\u01b0\u1ee3ng NAD+ hao h\u1ee5t \u0111i nhanh ch\u00f3ng. Bi\u1ec3u hi\u1ec7n c\u1ee7a vi\u1ec7c hao h\u1ee5t n\u00e0y ch\u00ednh l\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng suy gi\u1ea3m mi\u1ec5n d\u1ecbch c\u01a1 th\u1ec3 trong v\u00e0 sau Covid.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">B\u1eaft \u0111\u1ea7u t\u1eeb th\u1ef1c nghi\u1ec7m c\u1ee7a b\u00e1c s\u0129 Robert Huizenga, b\u1ec7nh vi\u1ec7n Cedars Sinai (Hoa K\u1ef3) \u0111\u00e3 cho b\u1ec7nh nh\u00e2n u\u1ed1ng NMN \u0111\u1ec3 l\u00e0m d\u1ecbu c\u01a1n b\u00e3o cytokine do COVID-19 g\u00e2y ra. NMN \u0111\u00e3 l\u00e0m h\u1ea1 s\u1ed1t v\u00e0 m\u1ee9c \u0111\u1ed9 vi\u00eam nhi\u1ec5m c\u1ee7a b\u1ec7nh nh\u00e2n trong v\u00f2ng 12 gi\u1edd. NMN \u0111\u00e3 \u0111\u01b0\u1ee3c \u00e1p d\u1ee5ng \u0111\u1ec3 duy tr\u00ec s\u1ef1 c\u00e2n b\u1eb1ng h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch, c\u00f3 th\u1ec3 l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb cho c\u01a1n b\u00e3o cytokine v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng h\u1eadu Covid do corona virus g\u00e2y ra.<\/span><\/p>\n<h2><span style=\"font-family: 'times new roman', times, serif;\"><strong>4. NMN c\u1ee7a CalerieHealth<\/strong><\/span><\/h2>\n<p><span style=\"font-family: 'times new roman', times, serif;\">\u00a0B\u0103\u0300ng c\u00f4ng ngh\u00ea\u0323 sinh ho\u0323c h\u01b0\u0303u c\u01a1 ti\u00ean ti\u00ea\u0301n, khoa ho\u0323c sinh ho\u0323c cho ra \u0111\u01a1\u0300i sa\u0309n ph\u00e2\u0309m <span style=\"color: #000000;\"><strong>\u03b2-<\/strong>N<\/span>MN 6.000 v\u00e0 SOD-NMN co\u0301 tha\u0300nh ph\u00e2\u0300n hoa\u0323t ch\u00e2\u0301t cao c\u00e2\u0301p \u03b2- NMN \u0111\u01b0\u01a1\u0323c khoa ho\u0323c u\u0309ng h\u00f4\u0323 nh\u01b0 m\u00f4\u0323t \u01b0\u0301ng c\u01b0\u0309 vi\u00ean \u0111\u00ea\u0309 ch\u00f4\u0301ng la\u0303o ho\u0301a va\u0300 ba\u0309o v\u00ea\u0323 th\u00e2\u0300n kinh.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><strong><span style=\"color: #ff0000;\"><span style=\"font-family: 'times new roman', times, serif;\">V\u01a1\u0301i c\u00f4ng tri\u0300nh nghi\u00ean c\u01b0\u0301u ha\u0300ng th\u00e2\u0323p ky\u0309 cu\u0309a y ho\u0323c v\u00ea\u0300 s\u01b0\u0323 s\u00f4\u0301ng t\u00ea\u0301 ba\u0300o. Ca\u0301c nha\u0300 khoa ho\u0323c pha\u0301t hi\u00ea\u0323n chi\u0309 co\u0301 \u03b2- NMN la\u0300 nguy\u00ean li\u00ea\u0323u ti\u00ea\u0301p \u01b0\u0301ng cho ca\u0301c ba\u0300o quan (ty th\u00ea\u0309,nhi\u00ea\u0303m s\u0103\u0301c th\u00ea\u0309,Ribosome&#8230;) t\u00f4\u0309ng h\u01a1\u0323p ra ca\u0301c CO-ENZYME (NAD+) \u00a0chu\u0309 l\u01b0\u0323c la\u0300m m\u00f4i tr\u01b0\u01a1\u0300ng xu\u0301c ta\u0301c, thu\u0301c \u0111\u00e2\u0309y ca\u0301c EZYME chuy\u00ea\u0309n ho\u0301a tham gia s\u01b0\u0309a ch\u01b0\u0303a, phu\u0323c h\u00f4\u0300i, la\u0300m m\u01a1\u0301i DNA.<\/span><\/span><\/strong><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\">\u00a0 <span style=\"color: #ff0000;\"><strong>\u03b2- NMN co\u0300n co\u0301 gia\u0301 tri\u0323 \u0111i\u0309nh cao l\u00e0 gi\u00fap ca\u0301c ba\u0300o quan t\u00f4\u0309ng h\u01a1\u0323p ca\u0301c c\u0103\u0323p ENZYM c\u01a1 s\u01a1\u0309 tham gia \u0111\u0103\u0301p va\u0301,s\u01b0\u0309a ch\u01b0\u0303a ca\u0301 l\u00f4\u0303 h\u00f4\u0309ng v\u1ecf bo\u0323c (telerme,ma\u0300ng sinh ch\u00e2\u0301t ) giu\u0301p cho t\u00ea\u0301 ba\u0300o tre\u0309 kho\u0309e s\u00f4\u0301ng l\u00e2u h\u01a1n.<\/strong><\/span><\/span><\/p>\n<p style=\"padding-left: 40px;\"><strong><span style=\"font-family: 'times new roman', times, serif; color: #ff0000;\">\u00a0\u03b2- NMN6,000 la\u0300m ch\u00e2\u0323m qua\u0301 tri\u0300nh la\u0303o ho\u0301a la\u0300nh ma\u0323nh. T\u0103ng m\u01b0\u0301c n\u0103ng l\u01b0\u01a1\u0323ng va\u0300 h\u00f4\u0303 tr\u01a1\u0323 ch\u01b0\u0301c n\u0103ng \u0111i\u00ea\u0300u khi\u00ea\u0309n \u0111e\u0309 co\u0301 m\u00f4\u0323t cu\u00f4\u0323c s\u00f4\u0301ng tre\u0309 \u0111e\u0323p va\u0300 kho\u0309e ma\u0323nh ma\u0300 chu\u0301ng ta x\u01b0\u0301ng \u0111a\u0301ng co\u0301 \u0111\u01b0\u01a1\u0323c.<\/span><\/strong><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">\u00a0 \u00a0 \u00a0 \u00a0 \u00a0D-GLUCAN la\u0300 go\u0301i mi\u00ea\u0303n di\u0323ch co\u0301 kha\u0309 n\u0103ng kha\u0301ng nhi\u00ea\u0303m n\u00e2\u0301m x\u00e2m l\u00e2\u0301n. Ba\u0309o v\u00ea\u0323 t\u00f4\u0301t cho h\u00ea\u0323 h\u00f4 h\u00e2\u0301p, di\u0323ch kh\u01a1\u0301p, di\u0323ch xoang, di\u0323ch c\u01a1 quan sinh du\u0323c.<\/span><span style=\"font-family: 'times new roman', times, serif;\">\u00a0 \u00a0 \u00a0 \u00a0\u00a0<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\">SOD l\u00e0 m\u1ed9t b\u1ed9 ph\u1eadn kh\u00f4ng th\u1ec3 thi\u1ebfu trong h\u1ec7 th\u1ed1ng ph\u00f2ng v\u1ec7 ch\u1ed1ng oxy h\u00f3a c\u1ee7a c\u01a1 th\u1ec3, v\u00e0 n\u00f3 \u0111\u00f3ng vai tr\u00f2 thi\u1ebft y\u1ebfu trong vi\u1ec7c duy tr\u00ec s\u1ee9c kh\u1ecfe v\u00e0 ch\u1ee9c n\u0103ng t\u1ebf b\u00e0o. SOD l\u00e0 enzyme ph\u1ed5 bi\u1ebfn, c\u00f3 m\u1eb7t trong t\u1ea5t c\u1ea3 c\u00e1c lo\u1ea1i t\u1ebf b\u00e0o v\u00e0 m\u00f4 trong c\u01a1 th\u1ec3, bao g\u1ed3m c\u1ea3 da, ph\u1ed5i, v\u00e0 n\u00e3o.\u00a0<\/span><span style=\"font-family: 'times new roman', times, serif;\">Superoxide dismutase (SOD) c\u00f3 nh\u1eefng \u0111\u1eb7c t\u00ednh quan tr\u1ecdng sau:<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>1. Ho\u1ea1t T\u00ednh Ch\u1ed1ng Oxy H\u00f3a:<\/strong> SOD l\u00e0 m\u1ed9t lo\u1ea1i enzyme m\u1ea1nh m\u1ebd v\u1edbi ho\u1ea1t t\u00ednh ch\u1ed1ng oxy h\u00f3a cao. SOD l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng oxy h\u00f3a t\u1ebf b\u00e0o r\u1ea5t quan tr\u1ecdng, gi\u00fap lo\u1ea1i b\u1ecf anion superoxide hi\u1ec7u qu\u1ea3, ch\u1ed1ng l\u1ea1i c\u00e1c g\u1ed1c t\u1ef1 do v\u00e0 gi\u00fap tr\u00ec ho\u00e3n qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a. N\u00f3 c\u00f3 kh\u1ea3 n\u0103ng chuy\u1ec3n \u0111\u1ed5i superoxide, m\u1ed9t ph\u00e2n t\u1eed oxy h\u00f3a g\u00e2y nguy h\u1ea1i, th\u00e0nh oxy v\u00e0 hydrogen peroxide (peroxit hydro), sau \u0111\u00f3 peroxit hydro s\u1ebd \u0111\u01b0\u1ee3c enzyme catalase chuy\u1ec3n h\u00f3a th\u00e0nh n\u01b0\u1edbc.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>2. B\u1ea3o V\u1ec7 T\u1ebf B\u00e0o:<\/strong> Nh\u1edd kh\u1ea3 n\u0103ng ch\u1ed1ng oxy h\u00f3a, SOD b\u1ea3o v\u1ec7 c\u00e1c t\u1ebf b\u00e0o kh\u1ecfi t\u1ed5n th\u01b0\u01a1ng do c\u00e1c g\u1ed1c t\u1ef1 do v\u00e0 stress oxy h\u00f3a g\u00e2y ra, \u0111\u1eb7c bi\u1ec7t l\u00e0 t\u1ed5n th\u01b0\u01a1ng li\u00ean quan \u0111\u1ebfn DNA, protein v\u00e0 m\u00e0ng t\u1ebf b\u00e0o.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>3. Quan Tr\u1ecdng Cho Vi\u1ec7c Ch\u1ed1ng L\u00e3o H\u00f3a:<\/strong> SOD \u0111\u01b0\u1ee3c xem l\u00e0 m\u1ed9t ph\u1ea7n quan tr\u1ecdng c\u1ee7a c\u01a1 ch\u1ebf ch\u1ed1ng l\u00e3o h\u00f3a c\u01a1 th\u1ec3, v\u00ec enzyme n\u00e0y gi\u1ea3m thi\u1ec3u t\u00e1c \u0111\u1ed9ng g\u1ed1c t\u1ef1 do c\u00f3 th\u1ec3 g\u00e2y ra vi\u1ec7c suy gi\u1ea3m ch\u1ee9c n\u0103ng t\u1ebf b\u00e0o v\u00e0 t\u0103ng t\u1ed1c \u0111\u1ed9 l\u00e3o h\u00f3a.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>4. Ch\u1ed1ng Vi\u00eam:<\/strong> SOD c\u0169ng c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m vi\u00eam trong c\u01a1 th\u1ec3 b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n qu\u00e1 tr\u00ecnh h\u00ecnh th\u00e0nh c\u1ee7a c\u00e1c ph\u00e2n t\u1eed c\u00f3 t\u00e1c d\u1ee5ng vi\u00eam nh\u01b0 peroxit hydro. C\u00e1c nghi\u00ean c\u1ee9u \u0111\u00e3 ph\u00e1t hi\u1ec7n ra r\u1eb1ng h\u00e0m l\u01b0\u1ee3ng SOD \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb vi\u00eam m\u00e3n t\u00ednh gi\u1ea3m \u0111\u00e1ng k\u1ec3 v\u00e0 gi\u1ea3m ho\u1ea1t \u0111\u1ed9ng. SOD c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m ph\u1ea3n \u1ee9ng Stress Oxy h\u00f3a v\u00e0 h\u1ea1n ch\u1ebf ph\u1ea3n \u1ee9ng ti\u1ec1n vi\u00eam.<\/span><\/p>\n<p style=\"text-align: left; padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>5. Ch\u1ed1ng quang h\u00f3a :<\/strong> SOD c\u00f3 th\u1ec3 b\u1ea3o v\u1ec7 T\u1ebf b\u00e0o v\u00e0 gi\u1ea3m t\u1ed5n th\u01b0\u01a1ng do tia c\u1ef1c t\u00edm g\u00e2y ra cho da ; n\u00f3 c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5c h\u1ed3i t\u1ed1t tr\u00ean v\u00f9ng da b\u1ecb b\u1ecfng ; c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5c h\u1ed3i t\u1ed1t \u0111\u1ed1i v\u1edbi v\u00f9ng da b\u1ecb t\u1ed5n th\u01b0\u01a1ng v\u00e0 c\u00e1c v\u1ebft th\u01b0\u01a1ng. SOD c\u00f3 th\u1ec3 gi\u00fap ph\u1ee5c h\u1ed3i v\u00e0 l\u00e0m m\u1ec1m c\u00e1c v\u1ebft s\u1eb9o.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>6. Ch\u1ed1ng Glycation:<\/strong> SOD c\u00f3 th\u1ec3 gi\u00fap gi\u1ea3m s\u1ef1 t\u00edch t\u1ee5 Carbohydrate trong c\u01a1 th\u1ec3 v\u00e0 k\u00edch ho\u1ea1t c\u00e1c T\u1ebf b\u00e0o \u0111\u1ea3o T\u1ee5y.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>7.Chi\u1ebfn \u0111\u1ea5u ch\u1ed1ng l\u1ea1i b\u1ec7nh suy n\u00e3o:<\/strong> SOD c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m Superoxide trong c\u01a1 th\u1ec3 n\u00e3o, do \u0111\u00f3 t\u0103ng c\u01b0\u1eddng tr\u00ed nh\u1edb v\u00e0 gi\u00fap tr\u00ec ho\u00e3n l\u00e3o h\u00f3a N\u00e3o .<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><strong>8.\u0110\u1ec1 kh\u00e1ng s\u1ef1 tho\u00e1i h\u00f3a c\u1ee7a c\u01a1 th\u1ec3 :<\/strong> S\u1ef1 t\u00edch t\u1ee5 c\u1ee7a c\u00e1c t\u1ed5n th\u01b0\u01a1ng do Oxy h\u00f3a t\u00e1c \u0111\u1ed9ng l\u00ean Ty th\u1ec3 \u0111\u01b0\u1ee3c coi l\u00e0 nguy\u00ean nh\u00e2n ch\u1ee7 y\u1ebfu khi\u1ebfn c\u01a1 th\u1ec3 con ng\u01b0\u1eddi b\u1ecb tho\u00e1i h\u00f3a v\u00e0 gi\u00e0 nua.<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">NMN c\u1ee7a Calerihealth \u0111\u01b0\u1ee3c t\u1ed5 ch\u1ee9c Submit \u0111\u00e1nh gi\u00e1 v\u1edbi ch\u1ee9ng nh\u1eadn \u0111\u1ea1t \u0111\u1ed9 thu\u1ea7n khi\u1ebft l\u00e0 99.92% \u03b2- NMN (<a href=\"https:\/\/drive.google.com\/file\/d\/1IM6FWzU06eU-5nFO2w_vsETWteFaKHoR\/view?usp=sharing\">XEM CH\u1ee8NG NH\u1eacN<\/a>), song song \u0111\u00f3 s\u1ea3n ph\u1ea9m c\u00f2n \u0111\u01b0\u1ee3c ch\u1ee9ng nh\u1eadn trong s\u00e1ch d\u01b0\u1ee3c \u0111i\u1ec3n PDR m\u1ed9t trong nh\u1eefng d\u01b0\u1ee3c th\u01b0 \u0111\u01b0\u1ee3c h\u00e0ng v\u1ea1n b\u00e1c s\u0129 tham kh\u1ea3o \u0111\u1ec3 k\u00ea \u0111\u01a1n \u0111i\u1ec1u tr\u1ecb cho b\u1ec7nh nh\u00e2n. Trong d\u01b0\u1ee3c th\u01b0 PDR t\u1ea1i th\u1eddi \u0111i\u1ec3m b\u00e0i vi\u1ebft n\u00e0y ch\u1ec9 c\u00f3 9 s\u1ea3n ph\u1ea9m ch\u1ee9a NMN trong s\u1ed1 h\u00e0ng ng\u00e0n s\u1ea3n ph\u1ea9m c\u00f3 tr\u00ean th\u1ecb tr\u01b0\u1eddng \u0111\u01b0\u1ee3c li\u1ec7t v\u00e0o ch\u1ee9ng th\u01b0 PDR, m\u00e0 s\u1ea3n ph\u1ea9m c\u1ee7a Calerie chi\u1ebfm \u0111\u1ebfn 2 s\u1ea3n ph\u1ea9m \u0111\u00f3 l\u00e0 NMN 6000 v\u00e0 SOD-NMN, \u0111\u00e2y l\u00e0 m\u1ed9t minh ch\u1ee9ng r\u00f5 cho ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m c\u1ee7a NMN.<\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2024\/05\/HINH-SUBMIT-99.92.png\" \/><\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>Ch\u1ee9ng nh\u1eadn Submit v\u1edbi \u0111\u1ed9 tinh khi\u1ebft <strong><span style=\"font-family: 'times new roman', times, serif;\">\u00a0\u03b2- NMN 99.92%<\/span><\/strong><\/em><\/span><\/p>\n<p><img decoding=\"async\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2024\/05\/chung-nhan-PDR-QR.png\" \/><\/p>\n<p style=\"text-align: center;\"><span style=\"font-size: 10pt;\"><em>NMN Calerie \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea trong d\u01b0\u1ee3c th\u01b0 PDR, trong 9 s\u1ea3n ph\u1ea9m ch\u1ee9a NMN l\u1ecdt v\u00e0o d\u01b0\u1ee3c th\u01b0 PDR th\u00ec NMN Calerie c\u00f3 2 s\u1ea3n ph\u1ea9m.<\/em><\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\"><a href=\"https:\/\/www.pdr.net\/full-prescribing-information\/hl\/?druglabelid=24424\">D\u01b0\u1ee3c th\u01b0 PDR c\u1ee7a M\u1ef9<\/a> : PDR \u0111\u01b0\u1ee3c ph\u00e2n ph\u1ed1i tr\u1ef1c ti\u1ebfp cho ph\u1ea7n l\u1edbn c\u00e1c b\u00e1c s\u0129 t\u1ea1i M\u1ef9, c\u0169ng nh\u01b0 \u0111\u01b0\u1ee3c ph\u1ed5 bi\u1ebfn trong c\u00e1c nh\u00e0 s\u00e1ch, th\u01b0 vi\u1ec7n v\u00e0 c\u00f3 gi\u00e1 tr\u1ecb l\u01b0u h\u00e0nh v\u00e0 s\u1eed d\u1ee5ng tr\u00ean to\u00e0n c\u1ea7u. C\u00e1c s\u1ea3n ph\u1ea9m \u0111\u1ec3 li\u1ec7t k\u00ea trong PDR, c\u1ea7n v\u01b0\u1ee3t qua \u0111\u01b0\u1ee3c c\u00e1c ki\u1ec3m tra v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng, hi\u1ec7u qu\u1ea3 s\u1eed d\u1ee5ng nghi\u00eam ng\u1eb7t nh\u1ea5t, \u0111\u1ed3ng th\u1eddi ph\u1ea3i kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 v\u00e0 \u0111\u1ea1t quy \u0111\u1ecbnh v\u1ec1 th\u1eddi gian l\u01b0u h\u00e0nh nh\u1eefng ti\u00eau chu\u1ea9n c\u1ee7a FDA, t\u1ea1i nh\u1eefng ph\u00f2ng th\u00ed nghi\u1ec7m, c\u00e1c vi\u1ec7n nghi\u00ean c\u1ee9u h\u00e0ng \u0111\u1ea7u tr\u1ef1c thu\u1ed9c h\u1ec7 th\u1ed1ng y t\u1ebf qu\u1ed1c gia Hoa K\u1ef3. Do \u0111\u00f3 PDR c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c xem l\u00e0 ngu\u1ed3n th\u00f4ng tin \u0111\u00e1ng tin c\u1eady nh\u1ea5t cho vi\u1ec7c xem x\u00e9t, tham kh\u1ea3o v\u00e0 l\u1ef1a ch\u1ecdn s\u1ea3n ph\u1ea9m \u0111\u1ec3 t\u01b0 v\u1ea5n cho b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng, ph\u1ee5c v\u1ee5 cho vi\u1ec7c \u0111i\u1ec1u tr\u1ecb hay h\u1ed7 tr\u1ee3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh l\u00fd, hay h\u1ed7 tr\u1ee3 ch\u0103m s\u00f3c v\u00e0 b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe. Theo th\u1ed1ng k\u00ea, ch\u1ec9 ri\u00eang t\u1ea1i n\u01b0\u1edbc M\u1ef9, trung b\u00ecnh m\u1ed7i tu\u1ea7n c\u00f3 h\u00e0ng tri\u1ec7u tri\u1ec7u l\u01b0\u1ee3t tham kh\u1ea3o th\u00f4ng tin s\u1ea3n ph\u1ea9m trong PDR t\u1eeb c\u00e1c b\u00e1c s\u0129 v\u00e0 c\u00e1c chuy\u00ean gia ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe nh\u1eb1m t\u01b0 v\u1ea5n cho b\u1ec7nh nh\u00e2n c\u1ee7a m\u00ecnh.<\/span><\/p>\n<p style=\"padding-left: 40px;\"><span style=\"font-family: 'times new roman', times, serif;\">Xem th\u00eam v\u1ec1 <a href=\"https:\/\/vi.wikipedia.org\/wiki\/Physicians%27_Desk_Reference\">d\u01b0\u1ee3c th\u01b0 PDR<\/a>:\u00a0 https:\/\/vi.wikipedia.org\/wiki\/Physicians%27_Desk_Reference.<\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #00ff00;\">\u00a0**************\u00a0 \u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660\u2660********************\u00a0<\/span><\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">V\u1edbi c\u00e1c ch\u1ee9ng nh\u1eadn t\u1eeb c\u00e1c t\u1ed5 ch\u1ee9c kh\u00e1c cho ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m nh\u01b0 ch\u1ee9ng nh\u1eadn Halla, ch\u1ee9ng nh\u1eadn thu\u1ea7n chay\u2026.c\u1ed9ng v\u1edbi m\u1ed9t s\u1ef1 \u0111\u1ea3m b\u1ea3o h\u00e0ng th\u1eadt \u0111\u01b0\u1ee3c chuy\u1ec3n t\u1eeb M\u1ef9 b\u1eb1ng m\u00e3 QR \u0111\u1eb7c tr\u01b0ng b\u1ea3o v\u1ec7 t\u1eebng s\u1ea3n ph\u1ea9m, gi\u00fap cho ng\u01b0\u1eddi d\u00f9ng th\u1ef1c s\u1ef1 an t\u00e2m khi s\u1eed d\u1ee5ng \u0111\u01b0\u1ee3c 1 s\u1ea3n ph\u1ea9m \u0111\u1eb3ng c\u1ea5p v\u00e0 \u0111\u00fang ch\u1ea5t l\u01b0\u1ee3ng x\u1ee9ng \u0111\u00e1ng v\u1edbi chi ph\u00ed b\u1ecf ra.<\/span><\/p>\n<p><strong>Xu\u1ea5t x\u1ee9:\u00a0 M\u1ef9,<\/strong>c\u00f3 tem QR truy xu\u1ea5t ngu\u1ed3n g\u1ed1c, th\u00f4ng tin m\u1ed7i l\u1ecd s\u1ea3n ph\u1ea9m ri\u00eang bi\u1ec7t <img decoding=\"async\" class=\"\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2023\/09\/QR.png\" width=\"80\" height=\"82\" \/><\/p>\n<p>M\u1ed7i m\u00e3 QR s\u1ebd \u0111\u01b0\u1ee3c m\u00e1y ch\u1ee7 c\u1ee7a c\u00f4ng ty qu\u1ea3n l\u00fd, v\u00e0 m\u1ed7i l\u1ea7n qu\u00e9t s\u1ebd \u0111\u01b0\u1ee3c ghi l\u1ea1i, l\u1ea7n qu\u00e9t \u0111\u1ea7u ti\u00ean s\u1ebd \u0111\u01b0\u1ee3c l\u01b0u gi\u1eef tr\u00ean h\u1ec7 th\u1ed1ng, bao g\u1ed3m ng\u00e0y gi\u1edd, v\u1ecb tr\u00ed v\u00e0 xu\u1ea5t x\u1ee9 ngu\u1ed3n g\u1ed1c s\u1ea3n ph\u1ea9m.<\/p>\n<p>Tem b\u1ea1c ch\u1ee9a m\u00e3 s\u1ea3n ph\u1ea9m s\u1ebd \u0111\u01b0\u1ee3c li\u00ean k\u1ebft v\u1edbi \u0111\u01a1n h\u00e0ng \u0111i\u1ec7n t\u1eed c\u1ee7a kh\u00e1ch h\u00e0ng khi \u0111\u1eb7t h\u00e0ng, v\u00e0 \u0111\u00e2y ch\u00ednh l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 \u0111\u1ec3 Calerie ch\u1ed1ng n\u1ea1n ph\u00e1 gi\u00e1, h\u00e0ng gi\u1ea3, m\u1ed9t trong nh\u1eefng n\u1ed7i \u0111au l\u1edbn c\u1ee7a th\u1ecb tr\u01b0\u1eddng hi\u1ec7n nay.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2023\/06\/chung-nhan-nmn.png\" \/><\/p>\n<h2><strong>C\u00e1c ch\u1ee9ng nh\u1eadn:<\/strong><\/h2>\n<p><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2024\/05\/chung-nhan-sod-nmn.png\" \/><\/p>\n<h2><strong>SOD-NMN &amp; NMN 6000 Calerie<\/strong><\/h2>\n<p><img decoding=\"async\" class=\"alignleft\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2023\/02\/NMN6K.png\" width=\"194\" height=\"194\" \/><\/p>\n<p><span style=\"font-size: 14pt;\"><strong>NMN6000: <\/strong><\/span><\/p>\n<p><strong>Ch\u1ee9a th\u00e0nh ph\u1ea7n \u03b2-Nicotinamide Mononucleotide<\/strong> (\u03b2-NMN) v\u1edbi h\u00e0m l\u01b0\u1ee3ng 6000mg\/ l\u1ecd, m\u1ed7i l\u1ecd g\u1ed3m 60 vi\u00ean, t\u00ednh ra th\u00e0nh ph\u1ea7n NMN ch\u1ee9a trong m\u1ed7i vi\u00ean l\u00e0 100mg\/vi\u00ean.<\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\"><strong>Ch\u1ee9a D-GLUCAN:<\/strong> la\u0300 go\u0301i mi\u00ea\u0303n di\u0323ch co\u0301 kha\u0309 n\u0103ng kha\u0301ng nhi\u00ea\u0303m n\u00e2\u0301m x\u00e2m l\u00e2\u0301n. Ba\u0309o v\u00ea\u0323 t\u00f4\u0301t cho h\u00ea\u0323 h\u00f4 h\u00e2\u0301p, di\u0323ch kh\u01a1\u0301p, di\u0323ch xoang, di\u0323ch c\u01a1 quan sinh du\u0323c.<\/span><span style=\"font-family: 'times new roman', times, serif;\">\u00a0 \u00a0 \u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><img decoding=\"async\" class=\"alignleft\" src=\"https:\/\/calerievn.com\/wp-content\/uploads\/2023\/02\/SODNMN.png\" width=\"211\" height=\"211\" \/><\/p>\n<p><span style=\"font-size: 14pt;\"><strong>SOD-NMN: 108.000 UI SOD &amp; 10.800mg NMN<\/strong><\/span><\/p>\n<p><strong>Ch\u1ee9a th\u00e0nh ph\u1ea7n \u03b2-Nicotinamide Mononucleotide<\/strong> (\u03b2-NMN) v\u1edbi h\u00e0m l\u01b0\u1ee3ng 10.800mg\/ l\u1ecd, m\u1ed7i l\u1ecd g\u1ed3m 90 vi\u00ean, t\u00ednh ra th\u00e0nh ph\u1ea7n NMN ch\u1ee9a trong m\u1ed7i vi\u00ean l\u00e0 120mg\/vi\u00ean.<\/p>\n<p><strong>Ch\u1ee9a th\u00e0nh ph\u1ea7n SOD<\/strong> v\u1edbi h\u00e0m l\u01b0\u1ee3ng 108.000 UI\/ l\u1ecd, m\u1ed7i l\u1ecd g\u1ed3m 90 vi\u00ean, t\u00ednh ra th\u00e0nh ph\u1ea7n SOD ch\u1ee9a trong m\u1ed7i vi\u00ean l\u00e0 24mg\/vi\u00ean.<\/p>\n<p>SOD -&#8220;V\u00c0NG D\u1ebaO C\u1ee6A BI\u1ec2N S\u00c2U&#8221; : Trung t\u00e2m nghi\u00ean c\u1ee9u 4Excelsior \u0111\u00e3 ph\u00e2n t\u00edch \u0111\u1eb7c t\u00ednh c\u1ea5u tr\u00fac c\u1ee7a m\u1ed9t lo\u00e0i t\u1ea3o \u01b0a nhi\u1ec7t bi\u1ec3n s\u00e2u, m\u1ed9t lo\u1ea1i T\u1ea3o \u01b0a nhi\u1ec7t v\u00f4 c\u00f9ng k\u1ef3 di\u1ec7u, n\u00f3 t\u1ed3n t\u1ea1i trong l\u00f2ng nh\u1eefng su\u1ed1i kho\u00e1ng d\u01b0\u1edbi \u0111\u00e1y \u0110\u1ea1i d\u01b0\u01a1ng c\u00f3 chi\u1ec1u s\u00e2u h\u01a1n 2.100m. Lo\u1ea1i t\u1ea3o \u01b0a nhi\u1ec7t n\u00e0y c\u00f3 th\u1ec3 t\u1ed3n t\u1ea1i \u1edf nhi\u1ec7t \u0111\u1ed9 464\u2103, n\u00f3 c\u00f3 kh\u1ea3 n\u0103ng ch\u1ecbu nhi\u1ec7t \u0111\u1ed9 cao, kh\u00e1ng Acid v\u00e0 kh\u00e1ng Ki\u1ec1m. C\u00e1c nh\u00e0 khoa h\u1ecdc s\u1eed d\u1ee5ng c\u00f4ng ngh\u1ec7 l\u00ean men \u0111\u01a1n b\u00e0o v\u00e0 c\u00f4ng ngh\u1ec7 tinh l\u1ecdc ph\u00e2n \u0111o\u1ea1n nh\u1ecf \u0111\u1ec3 ph\u00e2n l\u1eadp chi\u1ebft xu\u1ea5t SOD t\u1eeb lo\u1ea1i T\u1ea3o n\u00e0y, do \u0111\u00f3 \u0111\u1ea3m b\u1ea3o SOD Calerie t\u1ea1o ra t\u1eeb c\u00e1c lo\u1ea1i nguy\u00ean li\u1ec7u qu\u00ed v\u00e0 c\u1ef1c k\u1ef3 tinh khi\u1ebft v\u00e0 c\u00f3 nh\u1eefng hi\u1ec7u qu\u1ea3 kh\u00e1c bi\u1ec7t.<\/p>\n<p><span style=\"font-family: 'times new roman', times, serif;\">\u00a0<strong>Ch\u1ee9a D-GLUCAN:<\/strong> la\u0300 go\u0301i mi\u00ea\u0303n di\u0323ch co\u0301 kha\u0309 n\u0103ng kha\u0301ng nhi\u00ea\u0303m n\u00e2\u0301m x\u00e2m l\u00e2\u0301n. Ba\u0309o v\u00ea\u0323 t\u00f4\u0301t cho h\u00ea\u0323 h\u00f4 h\u00e2\u0301p, di\u0323ch kh\u01a1\u0301p, di\u0323ch xoang, di\u0323ch c\u01a1 quan sinh du\u0323c.<\/span><span style=\"font-family: 'times new roman', times, serif;\">\u00a0 \u00a0 \u00a0<\/span><\/p>\n<h2><strong>C\u00e1ch s\u1eed d\u1ee5ng:\u00a0<\/strong><\/h2>\n<p>D\u00f9ng m\u1ed7i ng\u00e0y t\u1eeb 2-3 vi\u00ean theo khuy\u1ebfn c\u00e1o c\u1ee7a nh\u00e0 s\u1ea3n xu\u1ea5t ghi tr\u00ean v\u1ecf h\u1ed9p<\/p>\n<p>Ng\u1eadm d\u01b0\u1edbi l\u01b0\u1ee1i, sau 20 gi\u00e2y h\u00e0m l\u01b0\u1ee3ng NDA+ trong t\u1ebf b\u00e0o \u0111\u01b0\u1ee3c sinh ra t\u1eeb NMN \u0111\u00e3 \u0111\u01b0\u1ee3c t\u0103ng l\u00ean, s\u1ea3n ph\u1ea9m \u0111i t\u1eeb \u0111\u1ed9ng m\u1ea1ch l\u01b0\u1ee1i, v\u00e0o m\u00e1u, \u0111\u1ebfn t\u1ebf b\u00e0o r\u1ea5t nhanh.<\/p>\n<p>V\u1edbi c\u00f4ng ngh\u1ec7 h\u1ea5p thu d\u01b0\u1edbi \u0111\u1ed9ng m\u1ea1ch l\u01b0\u1ee1i l\u00e0m cho s\u1ea3n ph\u1ea9m \u0111\u01b0\u1ee3c h\u1ea5p thu ho\u00e0n to\u00e0n &gt;99%, tr\u00e1nh \u0111\u01b0\u1ee3c d\u1ecbch axit d\u1ea1 d\u00e0y v\u00e0 kh\u00f4ng ph\u1ee5 thu\u1ed9c v\u00e0o s\u1ef1 h\u1ea5p th\u1ee5 c\u1ee7a ru\u1ed9t non nh\u01b0 c\u00e1c d\u1ea1ng s\u1ea3n ph\u1ea9m d\u1ea1ng vi\u00ean nang d\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng.<\/p>\n<p><iframe title=\"Gi\u1edbi thi\u1ec7u v\u1ec1 NMN6000\" width=\"640\" height=\"480\" src=\"https:\/\/www.youtube.com\/embed\/z9DK71t6eEg?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>[contact-form to=&#8221;calerieviet@gmail.com&#8221; subject=&#8221;calerieviet@gmail.com&#8221;][contact-field label=&#8221;H\u1ecd v\u00e0 T\u00ean&#8221; type=&#8221;name&#8221; required=&#8221;1&#8243;][contact-field label=&#8221;Email&#8221; type=&#8221;email&#8221; required=&#8221;1&#8243;][contact-field label=&#8221;S\u1ed1 \u0111i\u1ec7n tho\u1ea1i&#8221; type=&#8221;text&#8221; required=&#8221;1&#8243;][contact-field label=&#8221;B\u1ea1n c\u1ea7n t\u01b0 v\u1ea5n th\u00eam v\u1ec1 s\u1ea3n ph\u1ea9m g\u00ec?  h\u00e3y cho ch\u00fang t\u00f4i th\u00f4ng tin nh\u00e9&#8221; type=&#8221;textarea&#8221;][\/contact-form]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u1ed5ng quan NMN\u00a0 NMN l\u00e0 vi\u1ebft t\u1eaft c\u1ee7a Nicotinamide Mononucleotide, m\u1ed9t ch\u1ea5t ti\u1ec1n ch\u1ea5t c\u1ee7a Nicotinamide Adenine Dinucleotide (NAD+). NMN \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u v\u1edbi m\u1ee5c ti\u00eau gi\u1ea3m t\u00e1c \u0111\u1ed9ng c\u1ee7a l\u00e3o&#8230;<\/p>\n","protected":false},"author":1,"featured_media":237,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,4,5,7,27],"tags":[],"class_list":["post-604","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lam-dep","category-nmn","category-suc-khoe","category-tre-hoa","category-ung-thu"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NMN- D\u01af\u1ee2C CH\u1ea4T CH\u1ed0NG L\u00c3O H\u00d3A TO\u00c0N DI\u1ec6N - Ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe b\u1eaft \u0111\u1ea7u t\u1eeb t\u1ebf b\u00e0o<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/calerievn.com\/index.php\/2024\/05\/05\/tong-hop-ve-nmn\/\" \/>\n<meta property=\"og:locale\" content=\"vi_VN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NMN- D\u01af\u1ee2C CH\u1ea4T CH\u1ed0NG L\u00c3O H\u00d3A TO\u00c0N DI\u1ec6N - Ch\u0103m s\u00f3c s\u1ee9c kh\u1ecfe b\u1eaft \u0111\u1ea7u t\u1eeb t\u1ebf b\u00e0o\" \/>\n<meta property=\"og:description\" content=\"1. T\u1ed5ng quan NMN\u00a0 NMN l\u00e0 vi\u1ebft t\u1eaft c\u1ee7a Nicotinamide Mononucleotide, m\u1ed9t ch\u1ea5t ti\u1ec1n ch\u1ea5t c\u1ee7a Nicotinamide Adenine Dinucleotide (NAD+). 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